OK so I recently purchased a new PC with Windows Vista. I loaded all my old software onto the PC and most things seemed to work OK except for Top Producer 7i. No panic, Top Producer was always a pain to get up and running so I followed the suggestions in the help docs just like I have done in the past for XP machines. Still did not work. Last resort, I phoned tech support. They took me through a completely different set to options to change from those needed for XP and guess what it now works.
So to sum up Top Producer does work in Vista but you will need to call tech support to get it up and running.
Oh and just one more thing, my Windows Sidebar seems to have now stopped working. Now I wonder if one of the options I had to change for Top Producer caused this to stop working. Guess I need to do a bit more digging.